The pearlscale effect is caused by a mutation of the scale shape gene, which causes them to be malformed. It's a traditional recessive gene (a Punnett gene), in that both parents must carry it to pass it on.
The fish colour is carried on a separate gene loci, and is not directly related -- they're independent. So, yes, you can introduce the pearlscale gene into any colour group. But, you'll have to worry about the colour introduction from the pearlscale parents, and being that it's recessive, it might take a bit of "line breeding" to get it to resolve.